Stem Cell Transplant News

HOVON Trial: Autologous Stem Cell Transplant Remains Superior to Novel Agents for Treatment of Multiple Myeloma (October 12, 2016)

A large, comparative, phase III HOVON clinical trial recently confirmed that upfront autologous stem cell transplantation (ASCT) should still be the treatment of choice in younger patients with newly diagnosed multiple myeloma (MM). The findings of this... Continue Reading

Defitelio® Approved for Life-Threatening Complication of Stem Cell Transplant (March 30, 2016)

The United States Food and Drug Administration (FDA) has approved Defitelio® (defibrotide sodium) for the treatment of hepatic veno-occlusive disease (VOD) following a stem cell transplant. Defitelio is the first approved treatment for severe hepatic... Continue Reading

Myeloablative Treatment Regimens Superior to Reduced Intensity Treatment for AML and MDS Patients Undergoing Stem Cell Transplant (December 30, 2015)

Hematopoietic Stem Cell Transplant (SCT) is a standard and potentially curative treatment for individuals with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). Historically only high dose myeloablative treatment regimens were utilized since... Continue Reading

Prospective Study Shows Age Doesn’t Affect Survival Outcomes in Patients with Myelodysplastic Syndrome (MDS) Who Receive a Hematopoietic Cell Transplant (HCT) (December 14, 2015)

Results from a prospective study of 1,280 patients with myelodysplastic syndrome (MDS) showed that survival at 100 days and at two years following hematopoietic cell transplant (HCT) for patients aged 65 and older is comparable to patients aged 55 to... Continue Reading

Treatment with Early Stem Cell Transplant Improves Outcomes in Aggressive NHL (November 12, 2013)

Early autologous stem cell transplantation resulted in improved progression-free survival in patients with high-intermediate risk or high-risk disease who experienced a response to induction therapy, according to the results of a study published in the... Continue Reading

Zevalin Plus BEAM Chemotherapy Superior to BEAM Alone in Aggressive Lymphoma (March 22, 2013)

Standard-dose Zevalin® (ibritumomab tiuxetan) combined with BEAM high-dose chemotherapy is safe and possibly more effective than BEAM therapy alone as a conditioning regimen for autologous stem cell transplantation (ASCT), according to the results of... Continue Reading

Antiretroviral Drug May Prevent Graft-Versus-Host Disease (August 6, 2012)

The drug Selzentry® (maraviroc), which is typically used to treat HIV infection, may help prevent graft-versus-host disease (GVHD), a potentially lethal complication of stem cell transplants, according to the results of a study published in the New... Continue Reading

Mini-Transplants Continue to Show Promise for Older Patients with AML (November 10, 2011)

Less toxic cancer treatment followed by an allogeneic stem cell transplant is showing promise for older patients with advanced blood and bone marrow cancers such as acute myeloid leukemia (AML). These results were published in the Journal of the American... Continue Reading

Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)

A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading

Complementary Therapy for Children Undergoing Stem Cell Transplant (July 19, 2010)

Complementary therapies such as massage and humor therapy may not help children cope with the potential emotional distress associated with stem cell transplantation, according to findings recently reported in Cancer. Stem cell transplantation involves... Continue Reading

Latest Stem Cell Transplant News By Stage


Allogeneic Stem Cell Transplant

Myeloablative Treatment Regimens Superior to Reduced Intensity Treatment for AML and MDS Patients Undergoing Stem Cell Transplant (December 30, 2015)

Hematopoietic Stem Cell Transplant (SCT) is a standard and potentially curative treatment for individuals with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). Historically only high dose myeloablative treatment regimens were utilized since... Continue Reading

Antiretroviral Drug May Prevent Graft-Versus-Host Disease (August 6, 2012)

The drug Selzentry® (maraviroc), which is typically used to treat HIV infection, may help prevent graft-versus-host disease (GVHD), a potentially lethal complication of stem cell transplants, according to the results of a study published in the New... Continue Reading

Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)

A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading

Complementary Therapy for Children Undergoing Stem Cell Transplant (July 19, 2010)

Complementary therapies such as massage and humor therapy may not help children cope with the potential emotional distress associated with stem cell transplantation, according to findings recently reported in Cancer. Stem cell transplantation involves... Continue Reading

Statins May Reduce Acute Graft-versus-host Disease (March 8, 2009)

Statins May Reduce Acute Graft-versus-host Disease Researchers from Ohio State University have reported that statins may reduce the risk of developing acute graft-versus-host disease (GVHD) among patients who undergo allogeneic stem cell transplants.... Continue Reading

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Autologous Stem Cell Transplant

Treatment with Early Stem Cell Transplant Improves Outcomes in Aggressive NHL (November 12, 2013)

Early autologous stem cell transplantation resulted in improved progression-free survival in patients with high-intermediate risk or high-risk disease who experienced a response to induction therapy, according to the results of a study published in the... Continue Reading

Zevalin Plus BEAM Chemotherapy Superior to BEAM Alone in Aggressive Lymphoma (March 22, 2013)

Standard-dose Zevalin® (ibritumomab tiuxetan) combined with BEAM high-dose chemotherapy is safe and possibly more effective than BEAM therapy alone as a conditioning regimen for autologous stem cell transplantation (ASCT), according to the results of... Continue Reading

Complementary Therapy for Children Undergoing Stem Cell Transplant (July 19, 2010)

Complementary therapies such as massage and humor therapy may not help children cope with the potential emotional distress associated with stem cell transplantation, according to findings recently reported in Cancer. Stem cell transplantation involves... Continue Reading

Kepivance Reduces Toxicity of High-dose Therapy for Multiple Myeloma (March 24, 2010)

Among patients undergoing high-dose therapy and autologous stem cell transplantation for multiple myeloma, a three-day short course of Kepivance® (palifermin) reduces the toxicity of treatment. These results were published in the Annals of Oncology. Multiple... Continue Reading

Stem Cell Transplant Procedures Vary Throughout the World (March 8, 2009)

Stem Cell Transplant Procedures Vary Throughout the World Stem cell transplant practices vary substantially among physicians treating adults and children with hematologic malignancies (cancers of the blood or bone marrow such as leukemias and lymphomas).... Continue Reading

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